Dermaceutic Activ Retinol 1.0 - Intense Age Defense Serum

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RRP £50
- Skin appears smoother, more radiant and younger-looking.
- Ideal for mature skin.

Dermaceutic Activ Retinol 1.0 - Intense Age Defense Serum

Extra Strength. Supports the natural cell regeneration process and reduces the appearance of signs of skin aging. Activ Retinol 1.0 is recommended to treat loss of skin tone, wrinkles, fine lines and dull complexion.


Supports the natural cell regeneration process and reduces the appearance of signs of skin aging. Recommended for: loss of skin tone, wrinkles, fine lines and dull complexion. Mature skin.

A unique combination of high performance actives including skin restoring ceramides and cholesterol, hydrating actives Panthenol and Allantoin, and energizers containing essential minerals.

1% Retinol Complex
Repairs and protects damaged and dry skin. Stimulates the renewal of skin cells (basal layer) and regulates the migration and transformation of keratinocytes.

1% Pure Vitamins C & E
With renowned antioxidant properties, this combination of vitamins combats the signs of photoaging and limits their appearance.

Expert formula combining:
- Anti-wrinkle active: 1% Retinol Complex
- Antioxidant actives: 1% Pure Vitamins C & E
- Energizers: Essential Minerals
- Skin restoring Ceramides and Cholesterol
- Hydrating actives: Panthenol and Allantoin

The skin appears smoother, more radiant and younger-looking.

Ideal for For mature skin types
Apply to the face and neck in the evening after Dermaceutic cleanser
Then follow with Dermaceutic Hyal Ceutic

Caution : Retinol is a potent tool in treating photo-aged skin and may cause some irritation and sun sensitivity. so it is important to apply it at night and increase usage slowly and follow instructions.If you do experience any temporary mild irritation or flaking, either reduce frequency or increase additional hydrating/calming products to minimize the side effects.

Don't forget to always apply a high sunscreen daily.
Do not use if pregnant/breast feeding
Don't use products that contain Alpha Hydroxy Acid (AHA's), Salicylic Acid and Retinols if taking Roaccutane and for up to a year after you have stopped taking it.

If you would like some advice before using retinol please email

IngredientsAqua (water), Diglycerin PEG-40 Hydrogenated Castor Oil, Ethylhexyl Methoxycrylene, Panthenol, Retinol, Ascorbic Tetraisopalmate, Ascorbyl Palmiate, Tocopherol, Allantoin, Cholestrol, zinc PCA, Magnesium PCA, Sodium PCA, Sphingolipids, Phospholipids, lecithin, hydrogenated palm Glycerides Citrate, Polyacrylate Crosspolymer-6, Trideceth-9, Phenooxyethanol, Polysorbate 20, Ethylhexylglycerin, Propaneidiol, Disodium EDTA, T-butyl alcohol, BHT, potassium Sorbate, BHA, Cl

4.72 Average

32 Reviews

Rachel Rose

Excellent product , I advanced from 0 5 to 1.0 retinol , im 48 with some sun damage and fine lines , i simply would not have this in my skin care regime . It 100% improves skin texture, elasticity and firmness , people have commented on how " glowing" my skin is ❤

Catherine Genevie

This is a great product that really smooths out lines on my face. I had to work up to this strength though; it will cause flaking and redness if you don't start with the lesser strength (.3 or .5 to start, every other day for the first few weeks.) By the way, Retinol is something that the BBC has tested and states it has a positive impact on skin.

ilana Pinhas

After three weeks use it should be noted that the skin actually works red initially only where there is a stain but really not bad there is a gentle exfoliation which is good after two days the skin gets used and looks great feel a sense of tension and the face is bright and glowing

Lorraine Efune

I found that my skin was a little red after a few days of daily use. I then used it every alternate day. I can truly vouch for trhe difference in my skin .... Thank you Dermaceutic

ilana Pinhas

I tried a small area and did see a change since I have not been able to tell the end result but for a short time, but according to what I see, the preparation works and does the job

Enid Spira


I use it as a booster twice a a year. I find this works very well for me. I use one pump a night till it is gone.

Lisa Curran

I would recommend this product, skin felt less greasy and looked brighter.

Sotiria Galati

I love this serum! I have used retinol before but this one is beyond my expectations. Within a few days of using it, my skin looked brighter, less oily and more refined. About a week later it started peeling but much less than with other retinols. I haven't used it for a long time but I think it's wonderful.


The product arrived quickly (I ordered it from Germany) and seems to work as promised. Can’t comment on its effectiveness yet, I stopped the use in my face because it seems to strong for use in spring/summer. It is important to use a good sun blocker!!! At the moment I mix some drops with my bodymilk and this doesn’t irritate the skin. Though It’s quite pricey, I would buy it again.

Mrs L K Bourne

Good product, feels great on skin

Zainab Al Rahma

I like the product very much. It gives wonderful results on my skin. This is the 4th time I'm purchasing it.


Good product really

Anna Kormylo

A dermatologist friend of mine recommended this serum to me over a year ago and I having been using it since I have noticed a fabulous difference in the firmness of my skin it has also a lovely glow to it as well Highly recommend this product

Karla Martins

Michelle Somerston

susan Doust

Bought this serum for a friend, she is still using. Says that her skin appears smoother and tighter and will buy again.

Deborah Tokley

Highest concentration of Retinol I have found. Anything to help delay the ageing process, easily absorbed.


Very good product improoves skin tone

Deborah Tokley

Lightweight serum that absorbs into the skin quickly. I think its helping to keep the wrinkles at bay

Hanen Taieb

I lov lov that sirom from the first week I feel my skin changed I highly recommended Actually all dermaceutic products are amazing Thank you


Zainab Al Rahma

It helped in reducing the pores.

Rafael Vaillant

Best 1percent retinol!.....simple to understand what it is...other brands hide the retinol contents and oversell a trace amount as “best”.

Tom Willems


I use the serum each evening before bed. Initially it can cause the skin to be red and sensitive, but this is normal. Great product for mature skin.


Serum for the face that I bought in this company I liked. I use this serum in the morning before my moisturizer.Im not use in the night, because now i use retin -a, but after cup of weeks i wiil be use this serum night too. It amazing serum.


I have only used this product for a week but I like it so far. I don't see any difference yet but it is too soon. I like the way it doesn't take a lot of product to cover my neck and face. I look forward to seeing the result in about a month


Great product


Beautiful product used twice daily and keeps skin glowing throughout the day.

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